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Index > Protein center > Zeb1(Gene name) > Rat
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  • Zeb1 (Gene name),
  • Zinc finger E-box-binding homeobox 1 (Protein name ),  ZEB1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Zeb1(Tcf8);
    Protein name:
    Zinc finger E-box-binding homeobox 1;
    Alternative:
    Zinc finger homeodomain enhancer-binding protein(Zfhep);Transcription factor 8(TCF-8);
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts (via N-terminus) with SMARCA4/BRG1.
    Function:
    Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    1109
    Sequence:
    50:
    MADGPRCKRR | KQANPRRNNV | TNYNTVVEAN | SDSDDEDKLH | IVEEESVTDA | 
    100:
    ADCEGGVPDD | ELPTDQTVLP | GGSDRAGSAK | NCWQDDVKDD | ECDSDAENEQ | 
    150:
    NHDPNVEEFL | QQQDTAVIYP | EAPEEDQRQG | TPEASGHDDN | GTPDAFSQLL | 
    200:
    TCPYCDRGYK | RFTSLKEHIK | YRHEKNEDNF | SCSLCSYTFA | YRTQLERHMT | 
    250:
    SHKSGREQRH | VTQSGGNRKF | KCTECGKAFK | YKHHLKEHLR | IHSGEKPYEC | 
    300:
    PNCKKRFSHS | GSYSSHISSK | KCISLMPVNG | RPRSGLKTSQ | CSSPSLSTSP | 
    350:
    GSPTRPQIRQ | KIENKPLQEP | LSVNQIKTEP | VDYEFKPIVV | ASGINCSTPL | 
    400:
    QNGVFSGGGQ | LQATSSPQGV | VQAVVLPTVG | LVSPISINLS | DIQNVLKVAV | 
    450:
    DGNIIRQVLE | NNQASLASKE | QEAVSASSIQ | QGGHSVISAI | SLPLVDQDGT | 
    500:
    TKIIINYSLE | QPGQLQVVPQ | NLKKENPAPP | KSCKSEKSPE | DLTVKSEKDK | 
    550:
    SFDGAADEST | CLLCEDCPGD | LNALPELKHY | DPEHPAQPPP | PAPATEKPES | 
    600:
    SASSAGNGDL | SPSQPPLKNL | LSLLKAYYAL | NAQPSTEELT | KIADSVNLPL | 
    650:
    DVVKKWFEKM | QAGQIPGQSL | EPPSPGPGSG | NIPAKTEEQP | QPVDGNEPQE | 
    700:
    DSTRGQSPLK | MTSSPVLPVG | SAINGSRSCT | SSPSPLNLSS | ARNPQGYSCV | 
    750:
    SEGTQEEPQV | EPLDLSLPKQ | QGELLERSTV | SSVYQNSVYS | VQEEPLNLSC | 
    800:
    AKKEPQKDSC | VTDSEPVVNV | VPPSANPINI | AIPTVTAQLP | TIVAIADQNS | 
    850:
    VPCLRALAAN | KQTILIPQVA | YTYSATVSPA | MQEPPVKVIQ | PNGNQDERQD | 
    900:
    TSSEGVSVED | QNDSDCTPPK | KKTRKAENGM | YACDLCDKIF | QKSSSLLRHK | 
    950:
    YEHTGKRPHE | CGICRKAFKH | KHHLIEHMRL | HSGEKPYQCD | KCGKRFSHSG | 
    1000:
    SYSQHMNHRY | SYCKRGAEDR | DAMEQEDTGP | EALPEVLPTE | LVGARASPSQ | 
    1050:
    ADSDERESLT | REEDEDSEKE | EEEEDKEMEE | LQEDKECENP | QEEEEEEEEE | 
    1100:
    EEEEEEEEEE | EAEEAEHEAA | AAKTGGAVEE | EAAQQAGSFQ | QKASGSESKR | 
    1109:
    LSEEKTNEA
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Zinc finger E-box-binding homeobox 1
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    ELISA Kit for Rat Zinc finger E-box-binding homeobox 1
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    E14970h
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    ELISA Kit for Rat Zinc finger E-box-binding homeobox 1
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    ELISA Kit for Rat Zinc finger E-box-binding homeobox 1
    Cat.:
    E14970m
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    Packing:
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    CLIA Kit for Rat Zinc finger E-box-binding homeobox 1
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Zinc finger E-box-binding homeobox 1
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Zinc finger E-box-binding homeobox 1
    Cat.:
    U14970m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Zinc finger E-box-binding homeobox 1
    Cat.:
    U14970h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
    Polyclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
    Polyclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
    Polyclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
    Monoclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
    Monoclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
    Monoclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
    Monoclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
    Protein for Rat Zinc finger E-box-binding homeobox 1
    Protein for Rat Zinc finger E-box-binding homeobox 1
    Protein for Rat Zinc finger E-box-binding homeobox 1
    Protein for Rat Zinc finger E-box-binding homeobox 1

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    Precision
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    Linearity
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    References
    1. 1.
      "Alternative splicing gives rise to two isoforms of Zfhep, a zinc finger/homeodomain protein that binds T3-response elements."
      Cabanillas A.M. , Darling D.S.
      DNA Cell Biol.15:643-651(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 6-1109;ALTERNATIVE SPLICING
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