Protein name:
Zinc finger E-box-binding homeobox 1 ;
Alternative:
Zinc finger homeodomain enhancer-binding protein (Zfhep) ;Transcription factor 8 (TCF-8) ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Interacts (via N-terminus) with SMARCA4/BRG1.
Function:
Acts as a transcriptional repressor. Binds to E-box sequences in the immunoglobulin heavy chain enhancer as well as in the regulatory regions of many other tissue-specific genes. Represses E-cadherin promoter and induces an epithelial-mesenchymal transition (EMT) by recruiting SMARCA4/BRG1. Represses BCL6 transcription in the presence of the corepressor CTBP1. Positively regulates neuronal differentiation. Represses RCOR1 transcription activation during neurogenesis. Represses transcription by binding to the E box (5'-CANNTG-3'). Promotes tumorigenicity by repressing stemness-inhibiting microRNAs.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MADGPRCKRR | KQANPRRNNV | TNYNTVVEAN | SDSDDEDKLH | IVEEESVTDA |
100:
ADCEGGVPDD | ELPTDQTVLP | GGSDRAGSAK | NCWQDDVKDD | ECDSDAENEQ |
150:
NHDPNVEEFL | QQQDTAVIYP | EAPEEDQRQG | TPEASGHDDN | GTPDAFSQLL |
200:
TCPYCDRGYK | RFTSLKEHIK | YRHEKNEDNF | SCSLCSYTFA | YRTQLERHMT |
250:
SHKSGREQRH | VTQSGGNRKF | KCTECGKAFK | YKHHLKEHLR | IHSGEKPYEC |
300:
PNCKKRFSHS | GSYSSHISSK | KCISLMPVNG | RPRSGLKTSQ | CSSPSLSTSP |
350:
GSPTRPQIRQ | KIENKPLQEP | LSVNQIKTEP | VDYEFKPIVV | ASGINCSTPL |
400:
QNGVFSGGGQ | LQATSSPQGV | VQAVVLPTVG | LVSPISINLS | DIQNVLKVAV |
450:
DGNIIRQVLE | NNQASLASKE | QEAVSASSIQ | QGGHSVISAI | SLPLVDQDGT |
500:
TKIIINYSLE | QPGQLQVVPQ | NLKKENPAPP | KSCKSEKSPE | DLTVKSEKDK |
550:
SFDGAADEST | CLLCEDCPGD | LNALPELKHY | DPEHPAQPPP | PAPATEKPES |
600:
SASSAGNGDL | SPSQPPLKNL | LSLLKAYYAL | NAQPSTEELT | KIADSVNLPL |
650:
DVVKKWFEKM | QAGQIPGQSL | EPPSPGPGSG | NIPAKTEEQP | QPVDGNEPQE |
700:
DSTRGQSPLK | MTSSPVLPVG | SAINGSRSCT | SSPSPLNLSS | ARNPQGYSCV |
750:
SEGTQEEPQV | EPLDLSLPKQ | QGELLERSTV | SSVYQNSVYS | VQEEPLNLSC |
800:
AKKEPQKDSC | VTDSEPVVNV | VPPSANPINI | AIPTVTAQLP | TIVAIADQNS |
850:
VPCLRALAAN | KQTILIPQVA | YTYSATVSPA | MQEPPVKVIQ | PNGNQDERQD |
900:
TSSEGVSVED | QNDSDCTPPK | KKTRKAENGM | YACDLCDKIF | QKSSSLLRHK |
950:
YEHTGKRPHE | CGICRKAFKH | KHHLIEHMRL | HSGEKPYQCD | KCGKRFSHSG |
1000:
SYSQHMNHRY | SYCKRGAEDR | DAMEQEDTGP | EALPEVLPTE | LVGARASPSQ |
1050:
ADSDERESLT | REEDEDSEKE | EEEEDKEMEE | LQEDKECENP | QEEEEEEEEE |
1100:
EEEEEEEEEE | EAEEAEHEAA | AAKTGGAVEE | EAAQQAGSFQ | QKASGSESKR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Chicken
Mouse
ELISA Kit for Rat Zinc finger E-box-binding homeobox 1
ELISA Kit for Rat Zinc finger E-box-binding homeobox 1
ELISA Kit for Rat Zinc finger E-box-binding homeobox 1
ELISA Kit for Rat Zinc finger E-box-binding homeobox 1
CLIA Kit for Rat Zinc finger E-box-binding homeobox 1
CLIA Kit for Rat Zinc finger E-box-binding homeobox 1
CLIA Kit for Rat Zinc finger E-box-binding homeobox 1
CLIA Kit for Rat Zinc finger E-box-binding homeobox 1
Polyclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
Polyclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
Polyclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
Polyclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
Monoclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
Monoclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
Monoclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
Monoclonal Antibody for Rat Zinc finger E-box-binding homeobox 1
Protein for Rat Zinc finger E-box-binding homeobox 1
Protein for Rat Zinc finger E-box-binding homeobox 1
Protein for Rat Zinc finger E-box-binding homeobox 1
Protein for Rat Zinc finger E-box-binding homeobox 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 6-1109;ALTERNATIVE SPLICING